Gerhard Hamilton Selected Research

diamminedichlorodihydroxyplatinum IV

1/2017	In vitro Cytotoxic Activities of the Oral Platinum(IV) Prodrug Oxoplatin and HSP90 Inhibitor Ganetespib against a Panel of Gastric Cancer Cell Lines.
7/2014	Comparison of Intracellular Stress Response of NCI-H526 Small Cell Lung Cancer (SCLC) Cells to Platinum(II) Cisplatin and Platinum(IV) Oxoplatin.
1/2011	Comparison of the effects of the oral anticancer platinum(IV) complexes oxoplatin and metabolite cis-diammine-tetrachlorido-platinum(IV) on global gene expression of NCI-H526 cells.
8/2009	Characterization of chemosensitivity and resistance of human cancer cell lines to platinum(II) versus platinum(IV) anticancer agents.
1/2009	In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent.

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Gerhard Hamilton Research Topics

Disease

50	Neoplasms (Cancer) 06/2022 - 01/2009
22	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 06/2022 - 01/2009
9	Lung Neoplasms (Lung Cancer) 05/2022 - 10/2013
8	Breast Neoplasms (Breast Cancer) 02/2022 - 09/2003
8	Circulating Neoplastic Cells 01/2022 - 01/2015
7	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 10/2013
6	Neoplasm Metastasis (Metastasis) 02/2022 - 01/2015
5	Ovarian Neoplasms (Ovarian Cancer) 01/2021 - 01/2010
5	Prostatic Neoplasms (Prostate Cancer) 07/2012 - 09/2003
4	Inflammation (Inflammations) 08/2017 - 06/2015
3	Ewing Sarcoma (Sarcoma, Ewing) 06/2022 - 01/2010
3	Pleural Effusion (Pleural Effusions) 01/2022 - 01/2016
3	Colonic Neoplasms (Colon Cancer) 12/2021 - 01/2010
3	Carcinoid Tumor (Carcinoid) 01/2015 - 01/2010
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2011 - 06/2009
2	Type 2 Diabetes Mellitus (MODY) 02/2022 - 11/2020
2	Carcinoma (Carcinomatosis) 01/2021 - 09/2003
2	Stomach Neoplasms (Stomach Cancer) 01/2021 - 01/2017
2	Osteoporosis 09/2011 - 01/2010
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	Carcinogenesis 01/2021
1	Merkel Cell Carcinoma 01/2021
1	Cachexia 03/2016
1	Chronic Obstructive Pulmonary Disease (COPD) 06/2015
1	Glioblastoma (Glioblastoma Multiforme) 01/2015

Drug/Important Bio-Agent (IBA)

17	Pharmaceutical PreparationsIBA 06/2022 - 05/2003
14	PlatinumIBA 01/2022 - 01/2009
12	Cisplatin (Platino)FDA LinkGeneric 10/2018 - 01/2009
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2014
5	diamminedichlorodihydroxyplatinum IVIBA 01/2017 - 01/2009
4	Conditioned Culture MediaIBA 02/2022 - 09/2003
4	CytokinesIBA 01/2022 - 06/2015
4	EnzymesIBA 01/2019 - 11/2009
3	Tyrosine Kinase InhibitorsIBA 05/2022 - 01/2019
3	fascaplysineIBA 01/2022 - 03/2014
3	AntigensIBA 01/2019 - 12/2011
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2017 - 03/2010
3	Peptides (Polypeptides)IBA 01/2015 - 05/2003
3	Biological ProductsIBA 01/2015 - 01/2013
3	Platinum Compounds (Compounds, Platinum)IBA 10/2013 - 01/2010
3	AndrogensIBA 01/2013 - 01/2010
3	Hormones (Hormone)IBA 01/2013 - 04/2010
3	NeurotensinIBA 01/2011 - 06/2009
3	Interleukin-8 (Interleukin 8)IBA 01/2011 - 06/2009
2	Metformin (Glucophage)FDA LinkGeneric 02/2022 - 11/2020
2	AdipokinesIBA 02/2022 - 01/2021
2	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2017
2	avelumabIBA 01/2021 - 01/2017
2	Immunoglobulin G (IgG)IBA 01/2021 - 01/2017
2	Phosphotransferases (Kinase)IBA 01/2020 - 09/2003
2	Etoposide (VP 16)FDA LinkGeneric 01/2020 - 09/2012
2	VimentinIBA 01/2017 - 01/2010
2	ChitinasesIBA 06/2015 - 01/2015
2	Biomarkers (Surrogate Marker)IBA 01/2015 - 11/2009
2	amminedichloro(2- methylpyridine)platinum(II) (ZD0473)IBA 10/2013 - 05/2010
2	SteroidsIBA 01/2013 - 04/2010
2	XenobioticsIBA 09/2012 - 03/2011
2	Testosterone (Sustanon)FDA Link 09/2011 - 01/2010
2	satraplatin (JM 216)IBA 01/2011 - 05/2010
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2011 - 05/2010
2	Carboplatin (JM8)FDA LinkGeneric 01/2011 - 05/2010
2	Amiloride (Midamor)FDA LinkGeneric 03/2010 - 06/2009
2	Keratin-18 (Keratin 18)IBA 01/2010 - 11/2009
1	Proto-Oncogene Proteins c-metIBA 05/2022
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 05/2022
1	rovalpituzumab tesirineIBA 01/2022
1	Topotecan (Hycamtin)FDA LinkGeneric 01/2022
1	AfatinibIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 01/2022
1	BAY-293IBA 12/2021
1	Axitinib (AG 013736)IBA 01/2021
1	AngiopoietinsIBA 01/2021
1	Docetaxel (Taxotere)FDA Link 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Bevacizumab (Avastin)FDA Link 04/2020
1	Niclosamide FDA Link 01/2020
1	salinomycinIBA 01/2020
1	CathepsinsIBA 01/2019
1	Peptide Hydrolases (Proteases)FDA Link 01/2019
1	Oxygen (Dioxygen)IBA 01/2019
1	AntibodiesIBA 01/2019
1	Monoclonal AntibodiesIBA 01/2017
1	ChloridesIBA 01/2017
1	ProdrugsIBA 01/2017
1	STA 9090IBA 01/2017
1	Complement Factor D (Factor D)IBA 03/2016
1	vitamin D-binding protein-macrophage activating factorIBA 03/2016
1	Cadherins (E-Cadherin)IBA 01/2016
1	Epithelial Cell Adhesion MoleculeIBA 07/2015
1	CrizotinibIBA 05/2015
1	Capsules (Microcapsules)IBA 05/2015
1	ParaffinIBA 01/2015
1	AnionsIBA 01/2015
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2015

Therapy/Procedure

18	Drug Therapy (Chemotherapy) 06/2022 - 01/2010
16	Therapeutics 06/2022 - 01/2010
3	Immunotherapy 01/2021 - 01/2019
2	Withholding Treatment 09/2011 - 01/2010
1	Bioreactors (Bioreactor) 01/2022